Mabwell (SSE: 688062) is an innovation-driven biopharmaceutical company, has the entire industry chain of R&D, manufacturing, and commercialization. We committed to provide more effective and accessible therapy and innovative medicines to fulfill global medical needs.
Since 2017, an advanced R&D system which covers target discovery, early discovery, druggability, preclinical, clinical research and manufacturing transformation was established.
Mabwell has 14 pipeline products in different R&D stages based on a world-class and state-of-the-art R&D engine, including 10 novel drug candidates and 4 biosimilars. We focus on the therapeutic areas of auto-immune diseases, oncology, metabolic disorders, ophthalmologic diseases and infectious diseases, etc. Of these, 2 products have been approved and commercialized, 1 product has been filed for MA approval, 1 product is in the preparation of filing, 2 products are in pivotal trials. We have also undertaken 1 national major scientific and technological special project for "Significant New Drugs Development", 2 projects for National Key R&D Programmes, and several provincial and municipal science and technological innovation projects.
We strive for excellence in quality and apply rigorous management systems to ensure the high quality of every batch of products for patients. The Taizhou pilot and commercial manufacturing base is compliant with international GMP standards, and has passed the EU QP Audit. To satisfy the expanding R&D pipeline and production demands, we have built a large-scale commercial manufacturing base in Shanghai and an ADC commercialized manufacturing base in Taizhou.
9MW3011 FDA/NMPA approval for IND; agreement with DISC MEDICINE. Inc with total milestone up to $412.5 million.
2nd MA approval
MAILISHU, 2nd Denosumab biosimilar worldwide
Listing on the STAR Market
1st MA approval
JUNMAIKANG (Humira® biosimliar)
Series A financing
Industrial capability established
Taizhou manufacturing site in place
Initiate construction of Shanghai manufacturing site
Acquisition of PEG platform
Establish US innovation R&D site
Establish ADC platform
Integration of R&D resources
Establish high-throughput drug discovery platform
Initiate construction of Taizhou manufacturing site
LongRun Investment increased capital into Destiny Bio (New drug development dept. of Mabwell), improve the layout of antibody drug development.
M&A of T-mab & Kohnoor
National key research & development project, 2020 & 2021
Biomedical Science and Technology Support Special Project of Shanghai "Science & Technology Innovation Action Plan" in 2020 & 2021
High-tech Enterprises, 2022
Most innovative Global Biopharmaceutical Company
Included in the "List of New and Innovative Chinese Pharmaceutical Forces"
“Sci-Tech Innovation Board Leaders，2022
Biomedical innovation Golden Bud Award
Zhangjiang Life Science Industry New Prominent · 2022
Ranked the List of Top 20 Most Influential Antibody Pharmaceutical Companies in China 2022
TOP100 China Pharmaceutical Innovation Enterprise
TOP100 Companies in STAR Market
TOP100 Awards of Shanghai 1st High Value IP Operation Competition
Included in the “BIGStar 2021 Chinese Most Promising Innovative Biopharmaceutical Enterprises”
TOP30 China Antibody Drug Enterprises of Innovation , 2021 & 2020
BLDG 3, No 576, Libing Rd, Pudong New District, Shanghai, PRC
The Leading Talent of Shanghai biomedicine industry. The Evaluation Expert of National Science & Technology Award. The Evaluation Expert of National Major New Drug Innovation Program. The Expert of Talents Evaluation of Ministry of Industry & Information Technology of P.R.C. Vice Chairman of the council and member of the Expert Committee of the Society of Recombinant-Drugs of China Biochemical Pharmaceutical Industry Association. Secretary-General of Shanghai Industry Innovation Alliance of Biopharma (SIIAB).
Ph.D. of Pharmaceutical Chemistry from Shenyang Pharmaceutical University, Post doctor of Tumor Pharmacology from Institute of Materia Medica, Chinese academy of sciences, under two Academicians of Xinsheng Yao and Jian Ding.
Over 20 years of experience of R&D and industrialization of novel biologics. VP of the central research institute of Shanghai Pharma. GM of Shanghai Jiaolian Pharma. Deputy director, research institute of SINE.
Dr. Liu was responsible for around 10 major science projects including the 863 Program (National High-tech R&D Program), National Major Science and Technology Funding Projects, etc. Dr. Liu published over 20 academic papers with 5 patents granted.
Ph.D. in Pathology. R&D director of Tonghua Dongbao Pharmaceutical Co., Ltd. VP of Beijing CLKC Medicine Development Co., Ltd. CEO of Beijing Oriental TenGen Biomedical Co., Ltd. She has been working on R&D of novel drugs for over 20 years and has got about 20 IND and NDA applications approved. Led and participated in more than 10 National Major New Drug Innovation Program and other national research projects. More than 20 papers published and 16 patents granted. High-Level Innovation Talent in Jilin Province. Evaluation expert of Beijing Science and Technology Award. Well-experienced in business administration, Project management, HR and legal affairs management. Certified patent agent and expertise in patent strategies.
Ph.D. in biochemistry, Peking University. Post doctor in University of Texas Southwestern Medical Center, tutored by Nobel Laureate Dr. Bruce Beutler. Member of the International BioIron Society and American Society of Hematology. Principal scientist, COI Pharmaceutics. Assistant professor, UCSD. Assistant professor, The Scripps Research Institute. More than 20 years of experience in biomedical research and pharmaceutical R&D, covering a wide range of areas including hematology, iron metabolism, immunology, and cancer biology. More than 50 publications published with a cumulative impact factor of over 150.
Ph.D., Academy of Institute of biotechnology. Post doctor, University of Western Ontario. Expert in antibody drug discovery. Founder of Beijing Kohnoor Science & Technology Co., Ltd. Researcher in the Institute of biotechnology and Novo Nordisk. He has been working on the R&D and application of recombinant protein drugs & antibodies, and has rich experience in the generation of antibody drug engineering cell line and large-scale transient production, construction of large human antibody library, humanization of antibody and affinity maturation. He was involved in submitting FDA IND application of first biosimilar from China, and received 8 clinical trial approvals. 16 publications published and 2 patents granted.
Ph.D., Clinical Medicine, Fudan University. Professor of engineering. He worked as assistant to the president, director of clinical research center in Fosun Pharma Research Institute. Medical director, head of medical registration department and project management department in Sine Pharma (part of Shanghai Pharma Group). Over 15 years of experience in clinical research, scientific research management and team management. Expertise in GCP, drug registration regulations, clinical research strategies and plans, and overall managing experiment. Led and participated in over 10 clinical research projects, including National Major New Drug Innovation Programs and Shanghai Science and Technology Commission projects.
Master of Pharmaceutical Preparations, Shenyang Pharmaceutical University. He was GM of international business of 3S Pharmaceutical Group. GM of CN-GEN Mab. BD director & international business GM of CP GUOJIAN. Deputy director, director of international business, Sine Pharma (part of Shanghai Pharma Group). Rich experience in the fields of quality system, R&D management, BD, international RA and sales. Led ANDA projects, IND projects to US FDA and CTA projects to TGA. Principal head of National Major New Drug Innovation Program.
Ph.D. in biochemistry and molecular biology, Xiamen University. Postdoctoral fellow at UTHealth®, in U.S. Young Industrial Talent in "Shanghai Industrial Elite" high-level talent training program, 2022. He has the field of tumor biotherapeutics in 10 years R&D experience. During the postdoctoral research, he focused on the discovery of innovative drugs related to oncology, autoimmune and infectious diseases and participated in the early development of multiple innovative global therapeutic antibody drugs targeting the LILRB family. First-in-Class myeloid immune checkpoint inhibitor targeting LILRB4 granted fast track status by FDA for relapsed or refractory acute myeloid Leukemia.
More than 20 academic papers in Nature, Nature Communications, Cancer Immunology Research and other international journals, with a cumulative impact factor of over 300 and total citations of over 1,200. Over 40 patent applications summitted and 8 international patents granted.
Director of the Manufacturing dept., Hefei Zhaofeng Pharmacy. Assistant to chief engineer, Shanghai Wanxing Pharmacy. Project manager, GM, chief engineer, and GM of engineering management dept., 3S GUOJIAN. Deputy GM, GM of CMAB. He has long been engaged in the research and management of biopharmaceutical industrialization technology, with rich experiences in biopharmaceutical technology and equipment, system integration, large-scale biopharmaceutical process development and industrialization.
About 30 years of industry experience and 5 years of clinician in Tianjin Second Hospital. Previously worked in GSK, Sanofi, Tide and Kelun. National sales director in Sanofi, managing a thrombosis team of over 1,000 people, with a business scale of more than 3.5 billion. VP and GM of two business divisions in Tide, managing a team of about 2,000 people with a business scale of over 5 billion. VP in Kelun, in charge of the marketing and medical dept., and responsible for the establishment of the training and the SFE dept.
IMBA from Tongji University and Certified AICPA, IPA, CIA, 6-sigma Black Belt etc. He has over 15 years of experience in financial management work in both multi-national and top domestic pharmaceutical companies. Such as GE, J&J, Roche, Henlius. Prior to joining Mabwell, Mr. Hua was GM of finance & procurement of Henlius. Head of China manufacturing finance, Head of APAC product development & medical finance, Head of commercial finance (channel & pricing) in Roche. Rich experience in different finance functions like accounting, internal control, FPA, M&A, strategic planning, product portfolio management, biz model, etc.
Master of biochemistry and molecular biology, Jilin University. MBA, Shanghai Jiao Tong University. Prior to joining Mabwell, she worked for multi-national companies like GE Healthcare, Roche Diagnostics, Illumina and Thermo Fisher, etc. Great China commercial head, Illumina. National sales leader, life sciences of GE Healthcare. China sales & BD director, Veritas Genetics. Solid management experience in marketing, business development, and sales management in life science and biopharma industry.
Graduated from East China University of Science & Technology, major in chemical pharmacy. Previously Project head of CPIDI. Vice minister of investment planning for New Asiatic Pharmaceutical (part of Shanghai Pharma Group). Office supervisor, division head of investment plan, deputy general manager of investment development in strategy and investment committee of the board, Shanghai Pharmaceuticals Holding Co., Ltd. Deputy general manager of asset management, Deputy general manager of investment development, Shanghai pharmaceutical group Co., Ltd. Over 30 years of rich experience in biomedical industry construction and fixed assets management.